ISSCR News


Boosting Function and Survival of Stem Cell-derived Pancreatic Cells by Genetic Engineering
Keith Alm Keith Alm

Boosting Function and Survival of Stem Cell-derived Pancreatic Cells by Genetic Engineering

Recent advances in the transplantation of stem cell-derived insulin-producing beta cells (SC-beta cells) to treat type 1 diabetes (T1D) has generated considerable interest and excitement. A major obstacle to the long-term survival and functioning of SC-beta cells is their vulnerability to stress or attacks from the immune system, which can ultimately lead to malfunction or death of the cells. A recent study published in the journal Stem Cell Reports has identified new ways to potentially enhance the SC-beta cell survivability through genetic manipulation of the cells.

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The ISSCR Launches Standards Initiative for Pluripotent Stem Cell Research
Policy Keith Alm Policy Keith Alm

The ISSCR Launches Standards Initiative for Pluripotent Stem Cell Research

Universally accepted characterization standards for stem cell research are needed to improve the rigor and reproducibility of stem cell research. Standards set researchers up for success, ensure rigor in preclinical research, and ultimately strengthen the pipeline of therapies for patients. As the foremost international stem cell research society with a reputation for scientific and ethical rigor, the ISSCR is uniquely positioned to develop and propose research standards that can be widely adopted worldwide.

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